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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-Capstafin
Capstafin

Chemical Structure : Capstafin

CAS No.: 1818390-52-1

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Capstafin

货号: PC-61629Not For Human Use, Lab Use Only.

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.
    Capstafin displays 35-fold selectivity over the highly homologous STAT5a, >20-fold selectivity over STAT6, and >45-fold selectivity over STAT4.

    物理化学性质&存储条件

    分子量 453.365
    分子式 C17H29NO9P2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((8-methylnonanamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

    参考文献

    1. Elumalai N, et al. ACS Chem Biol. 2015 Dec 18;10(12):2884-90.

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