Capromorelin (CP-424391) | Ghrelin receptor agonist | Probechem Biochemicals

Chemical Structure : Capromorelin

CAS No.: 193273-66-4

加入收藏

Capromorelin (CP-424391, CP424391)

货号: PC-38623Not For Human Use, Lab Use Only.

Capromorelin (CP-424391) is a pyrazolinone-piperidine dipeptide growth hormone secretagogue and ghrelin receptor agonist with Ki value of 7 nM (hGHS-R1a), and EC50 vaule of 3 nM (rat pituicyte).

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2380	In stock
100 mg	￥3980	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Capromorelin (CP-424391) is a pyrazolinone-piperidine dipeptide growth hormone secretagogue and ghrelin receptor agonist with Ki value of 7 nM (hGHS-R1a), and EC50 vaule of 3 nM (rat pituicyte).
Capromorelin (CP-424391) increased plasma GH levels in an anesthesized rat model, with ED(50) values less than 0.05 mg/kg iv.
Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities

物理化学性质&存储条件

分子量	505.619
分子式	C28H35N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide

参考文献

1. Carpino PA, et al. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3279-82.

2. Pan LC, et al. Endocrine. 2001 Feb;14(1):121-32.

3. Carpino PA, et al. Bioorg Med Chem. 2003 Feb 20;11(4):581-90.

Capromorelin (CP-424391, CP424391)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Capromorelin (CP-424391, CP424391)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.