Chemical Structure : Caplacizumab
CAS No.: 915810-67-2
货号: PC-Ab1068Not For Human Use, Lab Use Only.
Caplacizumab (ALX0081) is a humanized single variable domain immunoglobulin (nanobody) against the von Willebrand factor (VWF). by targetting the A1 domain of the ultra-large von Willebrand factor which in order inhibits the interaction with the glycoprotein Ib-IX-V receptor in the platelets. Caplacizumab has used to treat acquired thrombotic thrombocytopenic purpura (aTTP)..
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Caplacizumab (ALX0081) is a humanized single variable domain immunoglobulin (nanobody) against the von Willebrand factor (VWF). by targetting the A1 domain of the ultra-large von Willebrand factor which in order inhibits the interaction with the glycoprotein Ib-IX-V receptor in the platelets. Caplacizumab has used to treat acquired thrombotic thrombocytopenic purpura (aTTP).
分子量 | ||
分子式 | Human Fc | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Caplacizumab; Cablivi; Caplacizumab-yhdp; ALX-0081; ALX0081; 915810-67-2; anti human von Willebrand factor; anti human vWF; human vWF nanobody |
1. 1, Bartunek J, et al. J Cardiovasc Transl Res. 2013 Jun;6(3):355-63. 2, Muller O, et al. J Cardiovasc Transl Res. 2013 Jun;6(3):364-70. 3, Peyvandi F, et al. N Engl J Med. 2016 Feb 11;374(6):511-22. 4, Scully M, et al. N Engl J Med. 2019 Jan 24;380(4):335-346.
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