Candoxatrilat |CAS:123122-54-3 Probechem Biochemicals

Chemical Structure : Candoxatrilat

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Candoxatrilat (UK 73967)

货号: PC-60711Not For Human Use, Lab Use Only.

A potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor that increases endogenous ANF levels and produces natriuretic and diuretic responses intravenously in mice..

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生物&药学活性

A potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor that increases endogenous ANF levels and produces natriuretic and diuretic responses intravenously in mice.

Heart Failure

Phase 1 Discontinued

物理化学性质&存储条件

分子量	399.484
分子式	C20H33NO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarbonyl]amino]cyclohexane-1-carboxylic acid

参考文献

1. Danilewicz JC, et al. Biochem Biophys Res Commun. 1989 Oct 16;164(1):58-65.

2. Shepperson NB, et al. Br J Pharmacol. 1989 Dec;98 Suppl:822P.

3. Jardine AG, et al. Am J Hypertens. 1990 Sep;3(9):661-7.

4. Northridge DB, et al. Lancet. 1989 Sep 9;2(8663):591-3.

Candoxatrilat (UK 73967)

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物理化学性质&存储条件

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Candoxatrilat (UK 73967)

生物&药学活性

物理化学性质&存储条件

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