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首页-小分子抑制剂&激动剂-GPCR-Angiotensin Receptor-Candesartan
Candesartan

Chemical Structure : Candesartan

CAS No.: 139481-59-7

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Candesartan (CV 11974, CV11974, CV-11974)

货号: PC-70201Not For Human Use, Lab Use Only.

Candesartan (CV-11974) is a potent, selective angiotensin II receptor antagonist, inhibits the binding of [125I] angiotensin II to the bovine adrenal cortical membrane and rabbit aortic membrane with IC50 of 112 nM and 28.6 nM, has potent and long-lasting antihypertensive effects.

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100 mg ￥1280 In stock
250 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Candesartan (CV-11974) is a potent, selective angiotensin II receptor antagonist, inhibits the binding of [125I] angiotensin II to the bovine adrenal cortical membrane and rabbit aortic membrane with IC50 of 112 nM and 28.6 nM, has potent and long-lasting antihypertensive effects.

物理化学性质&存储条件

分子量 440.45
分子式 C24H20N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid

参考文献

1. Shibouta Y, et al. J Pharmacol Exp Ther. 1993 Jul;266(1):114-20.

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