Chemical Structure : Camrelizumab
CAS No.: 1798286-48-2
货号: PC-Ab1118Not For Human Use, Lab Use Only.
Camrelizumab (HR 301210, INCSHR 1210, SHR 1210) is a humanised high-affinity IgG4-kappa monoclonal antibody that targets the programmed cell death protein 1 (PD-1), binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab blocks the binding of PD-1, expressed on activated T lymphocytes, B cells and natural killer (NK) cells, to its ligands programmed cell death ligand 1 (PD-L1), overexpressed on certain cancer cells, and p
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Camrelizumab (HR 301210, INCSHR 1210, SHR 1210) is a humanised high-affinity IgG4-kappa monoclonal antibody that targets the programmed cell death protein 1 (PD-1), binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab blocks the binding of PD-1, expressed on activated T lymphocytes, B cells and natural killer (NK) cells, to its ligands programmed cell death ligand 1 (PD-L1), overexpressed on certain cancer cells, and programmed cell death ligand 2 (PD-L2), which is primarily expressed on antigen presenting cells (APCs).
分子量 | ||
分子式 | Human IgG4 (S228P)-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Camrelizumab; SHR-1210; SHR1210; HR 301210, INCSHR 1210; 1798286-48-2; Anti-human programmed death receptor-1; Anti-human PD1 |
1. 1, Zhou C, et al. Lancet Respir Med. 2021 Mar;9(3):305-314. 2, Xu J, et al. Clin Cancer Res. 2021 Feb 15;27(4):1003-1011. 3, Lan C, , et al. J Clin Oncol. 2020 Dec 1;38(34):4095-4106. 4, Xu J, et al. Clin Cancer Res. 2019 Jan 15;25(2):515-523. 5, Huang J, et al. Cancer. 2019 Mar 1;125(5):742-749.
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