Camostat

Chemical Structure : Camostat

CAS No.: 59721-28-7

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货号: PC-24582Not For Human Use, Lab Use Only.

Camostat is a trypsin-like protease inhibitor, also is a TMPRSS2 inhibitor, inhibits SARS-CoV-2 infection.

规格	价格	库存
25 mg	￥480	In stock
100 mg	￥980	In stock
250 mg	￥1480	In stock
1 g		Get quote

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生物&药学活性

Camostat is a trypsin-like protease inhibitor, also is a TMPRSS2 inhibitor, inhibits SARS-CoV-2 infection.
Camostat is a potent (IC(50) approximately 50 nM) and prolonged attenuation of ENaC function in human airway epithelial cell models.
Camostat reduces pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decreases the proliferation and activation of pancreatic stellate cells (PSCs).

物理化学性质&存储条件

分子量	398.42
分子式	C20H22N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate

参考文献

1. Ohkoshi M. Gan. 1981 Dec;72(6):959-64.

2. Mahoney M, et al. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108728118.

3. Coote K, et al. J Pharmacol Exp Ther. 2009 May;329(2):764-74.

Camostat

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物理化学性质&存储条件

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Camostat

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