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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-Calyculin A
Calyculin A

Chemical Structure : Calyculin A

CAS No.: 101932-71-2

Calyculin A ((-)-Calyculin A)

货号: PC-45587Not For Human Use, Lab Use Only.

Calyculin A is a more potent phosphatase inhibitor than Okadaic acid, inhibits catalytic subunit of type-2A phosphatase (IC50 =0.5-1 nM), calyculin A is more effective for protein phosphatase type-1.

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25 ug ¥2480 In stock
100 ug ¥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Calyculin A is a more potent phosphatase inhibitor than Okadaic acid, inhibits catalytic subunit of type-2A phosphatase (IC50 =0.5-1 nM), calyculin A is more effective for protein phosphatase type-1.

物理化学性质&存储条件

分子量 1009.17
分子式 C50H81N4O15P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Ribonamide, N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraen-1-yl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-pr

参考文献

1. Ishihara H, et al. Biochem Biophys Res Commun. 1989 Mar 31;159(3):871-7.

2. Resjö S, et al. Biochem J. 1999 Aug 1;341 ( Pt 3):839-45.

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