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Caf1 inhibitor 8j

Chemical Structure : Caf1 inhibitor 8j

CAS No.: 1807775-88-7

Caf1 inhibitor 8j

货号: PC-20454Not For Human Use, Lab Use Only.

Caf1 inhibitor 8j is a potent, selective inhibitor of human poly(A)-selective ribonuclease Caf1 with IC50 of 0.59 uM, 40-fold selectivity over the related deadenylase PARN.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Caf1 inhibitor 8j is a potent, selective inhibitor of human poly(A)-selective ribonuclease Caf1 with IC50 of 0.59 uM, 40-fold selectivity over the related deadenylase PARN.

    物理化学性质&存储条件

    分子量 357.41
    分子式 C18H23N5O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-(3-(dimethylamino)propyl)-1-hydroxy-7-phenethyl-3,7-dihydro-1H-purine-2,6-dione

    参考文献

    1. Gopal P Jadhav, et al. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4219-24.

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