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CaMKII-IN-1

Chemical Structure : CaMKII-IN-1

CAS No.: 1208123-85-6

CaMKII-IN-1 (CaMKII inhibitor)

货号: PC-45443Not For Human Use, Lab Use Only.

CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM.

规格 价格 库存 数量
5 mg ¥1380 In stock
10 mg ¥2280 In stock
25 mg ¥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM.
CaMKII-IN-1 shows no inhibitory effect for CaMKIV, MLCK, p38α, Akt1, PKC etc.
CaMKII-IN-1 shows 25-fold higher potency than KN-93.

物理化学性质&存储条件

分子量 548.0988
分子式 C29H30ClN5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 54 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-

参考文献

1. Asano S, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.

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