CaMK1D-IN-18

Chemical Structure : CaMK1D-IN-18

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货号: PC-72908Not For Human Use, Lab Use Only.

CaMK1D-IN-18 is a potent, selective CaMK1D inhibitor with IC50 of 31 nM, >150-fold greater activity against CaMK1D than all non-CaMK1 kinases.

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生物&药学活性

CaMK1D-IN-18 is a potent, selective CaMK1D inhibitor with IC50 of 31 nM, >150-fold greater activity against CaMK1D than all non-CaMK1 kinases.
CaMK1D-IN-18 improves insulin sensitivity and glucose control in the diet-induced obesity mouse model after both acute and chronic administration.

物理化学性质&存储条件

分子量	483.017
分子式	C24H31ClN8O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(3-Aminopiperidin-1-yl)-4-((3,5-bis(2-cyanopropan-2-yl)phenyl)amino)pyrimidine-5-carboxamide Hydrochloride

参考文献

1. Christophe Fromont, et al. J Med Chem. 2020 Jul 9;63(13):6784-6801.

CaMK1D-IN-18

生物&药学活性

物理化学性质&存储条件

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CaMK1D-IN-18

生物&药学活性

物理化学性质&存储条件

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