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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Other Viruses-CZV1-1
CZV1-1

Chemical Structure : CZV1-1

CAS No.:

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CZV1-1

货号: PC-22896Not For Human Use, Lab Use Only.

CZV1-1 is a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope., purified anti-CZV1-1 IgG neutralizes infection of ZIKV in cell cultures with potencies comparable to highly specific ZIKV-neutralizing mAbs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CZV1-1 is a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope., purified anti-CZV1-1 IgG neutralizes infection of ZIKV in cell cultures with potencies comparable to highly specific ZIKV-neutralizing mAbs.
CZV1-1 mimics a nonlinear, neutralizing conformational epitope in the domain III of the ZIKV envelope.

物理化学性质&存储条件

分子量 1152.32
分子式 C62H73N9O13
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-3-((1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)-N-(4-(2-(3-((1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzamido)-13-(2-amino-2-oxoethyl)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3,12-dioxo-7,10-dioxa-4,13-diazahexadec-15-yn-1-yl)phenyl)-N-((1H-imidazol-2-yl)methyl)benzamide

参考文献

1. Castanha PMS, et al. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2312755121.

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