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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Polo-like Kinase (PLK)-CZS-089
CZS-089

Chemical Structure : CZS-089

CAS No.:

CZS-089 (CZS089)

货号: PC-25891Not For Human Use, Lab Use Only.

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

物理化学性质&存储条件

分子量 503.51
分子式 C24H18FN7O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea

参考文献

1. Yin Sun, et al. J Med Chem. 2023 Feb 23;66(4):2396-2421.

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