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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Bcr-Abl-CZC-8004
CZC-8004

Chemical Structure : CZC-8004

CAS No.: 916603-07-1

CZC-8004 (CZC-00008004;CZC8004;Dianilinopyrimidine-01)

货号: PC-60538Not For Human Use, Lab Use Only.

CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations.

物理化学性质&存储条件

分子量 309.3
分子式 C17H16FN5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N2-​[4-​(aminomethyl)​phenyl]​-​5-​fluoro-​N4-​phenyl-2,​4-​pyrimidinediamine

参考文献

1. Klutchko SR, et al. J Med Chem. 1998 Aug 13;41(17):3276-92.

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