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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-RAD51-CYT-0851
CYT-0851

Chemical Structure : CYT-0851

CAS No.: 2301085-04-9

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CYT-0851 (Emzadirib, CYT0851)

货号: PC-22006Not For Human Use, Lab Use Only.

CYT-0851 (Emzadirib) is a potent, selective and oral inhibitor of RAD51-mediated DNA repair, inhibits homologous recombination (HR) leading to an accumulation of unrepaired DSBs and tumor cell death.

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5 mg ￥3880 In stock
10 mg ￥5880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CYT-0851 (Emzadirib) is a potent, selective and oral inhibitor of RAD51-mediated DNA repair, inhibits homologous recombination (HR) leading to an accumulation of unrepaired DSBs and tumor cell death.

物理化学性质&存储条件

分子量 580.76
分子式 C27H40N4O6S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

isopropyl (3-(N-(tert-butyl)sulfamoyl)-4-(2-((1r,4r)-4-((isopropoxycarbonyl)amino)cyclohexyl)thiazol-5-yl)phenyl)carbamate

参考文献

1. Ryan C Lynch, et al. Journal of Clinical Oncology, 2021. Volume 39, Number 15_suppl.

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