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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-CX614
CX614

Chemical Structure : CX614

CAS No.: 191744-13-5

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CX614 (CX-614)

货号: PC-61704Not For Human Use, Lab Use Only.

CX614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease.

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25 mg ￥880 In stock
50 mg ￥1280 In stock
100 mg ￥1880 In stock
250 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CX614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease.
CX614 has also been shown to reduce the behavioural effects of methamphetamine in mice.

物理化学性质&存储条件

分子量 247.25
分子式 C13H13NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one

参考文献

1. Arai AC, et al. Mol Pharmacol. 2000 Oct;58(4):802-13.

2. Dicou E, et al. Brain Res. 2003 Apr 25;970(1-2):221-5.

3. Lauterborn JC, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):297-305.

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