Chemical Structure : CU7218
CAS No.: 34330-04-6
货号: PC-72267Not For Human Use, Lab Use Only.
CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3.
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CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3.
CU7218 displaces FOXO3a and other substrate proteins from 14-3-3 and reproduces the cellular phenotypes induced by 9J10 expression.
分子量 | 242.267 | |
分子式 | C8H6N2O3S2 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
1,2,3,4-Tetrahydro-5-methyl-4-oxo-2-thioxothieno[2,3-d]pyrimidine-6-carboxylic acid |
1. Amy Emery, et al. Cell Chem Biol. 2021 Nov 18;28(11):1602-1615.e9.
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