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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-CU-115
CU-115

Chemical Structure : CU-115

CAS No.: 2471982-20-2

CU-115 (CU115)

货号: PC-72052Not For Human Use, Lab Use Only.

CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).

物理化学性质&存储条件

分子量 569.217
分子式 C21H11F7INO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-

参考文献

1. Rosaura Padilla-Salinas, et al. J Med Chem. 2019 Nov 27;62(22):10221-10244.

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