CTS-1027 |CAS:193022-04-7 Probechem Biochemicals

Chemical Structure : CTS-1027

CAS No.: 193022-04-7

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CTS-1027 (RS-130830, Ro-1130830, CTS1027)

货号: PC-42562Not For Human Use, Lab Use Only.

CTS-1027 (RS-130830) is a potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14, but not MMP1 and 7.

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10 mg	￥2180	In stock
25 mg	￥3680	In stock
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100 mg		Get quote

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生物&药学活性

CTS-1027 (RS-130830) is a potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14, but not MMP1 and 7.
CTS-1027 displays little or no activity for other proteinases including caspases, the initiator and effector proteinases of apoptosis.
CTS-1027 attenuates hepatocyte apoptosis, liver injury and hepatic fibrosis, and is an attractive agent as a potential hepato-protective agent in HCV patients.

物理化学性质&存储条件

分子量	425.8832
分子式	C19H20ClNO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-Pyran-4-carboxamide, 4-[[[4-(4-chlorophenoxy)phenyl]sulfonyl]methyl]tetrahydro-N-hydroxy-

参考文献

1. Kahraman A, et al. Hepatol Res. 2009 Aug;39(8):805-13.

2. Liechti FD, et al. J Neuroinflammation. 2015 Mar 4;12:43.

CTS-1027 (RS-130830, Ro-1130830, CTS1027)

生物&药学活性

物理化学性质&存储条件

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CTS-1027 (RS-130830, Ro-1130830, CTS1027)

生物&药学活性

物理化学性质&存储条件

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