CTPI-2 | SLC25A1 inhibitor | Probechem Biochemicals

Chemical Structure : CTPI-2

CAS No.: 68003-38-3

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CTPI-2 (SLC25A1 inhibitor CTPI-2)

货号: PC-35588Not For Human Use, Lab Use Only.

CTPI-2 (SLC25A1 inhibitor CTPI-2) is a novel specific SLC25A1 inhibitor with Kd of 3.5 uM, CTPI-2 is synthetic lethal with cisplatin or with EGFR inhibitor co-treatment and restores antitumor responses both in vitro and in vivo.

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100 mg	￥580	In stock
250 mg	￥880	In stock
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生物&药学活性

CTPI-2 (SLC25A1 inhibitor CTPI-2) is a novel specific SLC25A1 inhibitor with Kd of 3.5 uM, CTPI-2 is synthetic lethal with cisplatin or with EGFR inhibitor co-treatment and restores antitumor responses both in vitro and in vivo.
CTPI-2 disrupts self-renewal and sphere-forming capacity of the indicated tumor cells relative to monolayer cultures, demonstrates broad activity on lung CSCs, inhibiting mitochondrial respiratory activity, self-renewal and matrix invasion.
CTPI-2 inhibits tumor growth in in vivo models of NSCLC.

物理化学性质&存储条件

分子量	356.733
分子式	C13H9ClN2O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-chloro-3-nitrophenyl)sulfonamido)benzoic acid

参考文献

1. Fernandez HR, et al. Cell Death Differ. 2018 Jul;25(7):1239-1258.

CTPI-2 (SLC25A1 inhibitor CTPI-2)

生物&药学活性

物理化学性质&存储条件

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CTPI-2 (SLC25A1 inhibitor CTPI-2)

生物&药学活性

物理化学性质&存储条件

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