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首页-小分子抑制剂&激动剂-Epigenetics-Histone Acetyltransferase (HAT)-CTPB
CTPB

Chemical Structure : CTPB

CAS No.: 586976-24-1

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CTPB (p300 activator CTPB)

货号: PC-62266Not For Human Use, Lab Use Only.

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B), which enhanced HAT-dependent transcriptional activation.

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10 mg ￥3280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B), which enhanced HAT-dependent transcriptional activation.
CTPB has no effect on histone deacetylase activity.
CTPB promotes the survival and neurite growth of the SH-SY5Y cells, and also protects these cells from cell death induced by the neurotoxin 6-hydroxydopamine.

物理化学性质&存储条件

分子量 554.135
分子式 C31H43ClF3NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide

参考文献

1. Balasubramanyam K, et al. J Biol Chem. 2003 May 23;278(21):19134-40.

2. Hegarty SV, et al. Neurotox Res. 2016 Oct;30(3):510-20.

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