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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-CTCE-9908
CTCE-9908

Chemical Structure : CTCE-9908

CAS No.: 1030384-98-5

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CTCE-9908 (CTCE9908)

货号: PC-23668Not For Human Use, Lab Use Only.

CTCE-9908 is a potent and selective CXCR4 antagonist, induces mitotic catastrophe in ovarian cancer cells.

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5 mg ￥3980 In stock
10 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CTCE-9908 is a potent and selective CXCR4 antagonist, induces mitotic catastrophe in ovarian cancer cells.
CTCE-9908 inhibits migration and growth in CXCR4-expressing ovarian cancer cells.
CTCE-9908 induces multinucleation and G2-M arrest in ovarian cancer cells.
CTCE-9908 induces DNA re-replication and abnormal mitoses in ovarian cancer cells.
CTCE-9908 significantly reduced lung metastasis of osteosarcoma and melanoma cells in animal models.

物理化学性质&存储条件

分子量 1927.29
分子式 C86H147N27O23
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

L-Lysinamide, N2,N6-bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-

参考文献

1. Kim SY, et al. Clin Exp Metastasis. 2008;25(3):201-11.

2. Porvasnik S, et al. Prostate. 2009 Sep 15;69(13):1460-9.

3. Kwong J, et al. Mol Cancer Ther. 2009 Jul;8(7):1893-905.

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