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首页-小分子抑制剂&激动剂-Others-Other Targets-CSE inhibitor 43
CSE inhibitor 43

Chemical Structure : CSE inhibitor 43

CAS No.: 2190517-61-2

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CSE inhibitor 43

货号: PC-72154Not For Human Use, Lab Use Only.

CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.
    CSE inhibitor 43 displays high selectivity versus cystathionine β-synthase (CBS, >400-fold selectivity over).
    CSE inhibitor 43 is potentially valuable pharmacological tool for the study of H2S signaling.

    物理化学性质&存储条件

    分子量 378.44
    分子式 C16H15FN4O2S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-((4-methoxyphenyl)amino)-2-oxoethyl (E)-2-((3-fluoropyridin-2-yl)methylene)hydrazine-1-carbodithioate

    参考文献

    1. Bhattacharjee A, ACS Med Chem Lett. 2017 Nov 21;8(12):1241-1245.

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