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首页-小分子抑制剂&激动剂-Apoptosis-IAP-CS3
CS3

Chemical Structure : CS3

CAS No.: 1207457-11-1

CS3 (cIAP inhibitor CS3)

货号: PC-62350Not For Human Use, Lab Use Only.

CS3 is a potent, selective cIAP1 and cIAP2 inhibitor with IC50 of 16 nM and 85 nM respectively, shows no significant activity against XIAP (IC50>34 uM)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CS3 is a potent, selective cIAP1 and cIAP2 inhibitor with IC50 of 16 nM and 85 nM respectively, shows no significant activity against XIAP (IC50>34 uM).

    物理化学性质&存储条件

    分子量 506.651
    分子式 C28H38N6O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (2S,3S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-3-methyl-N-(2-(pyrimidin-2-yl)phenyl)pyrrolidine-2-carboxamide

    参考文献

    1. Ndubaku C, et al. ACS Chem Biol. 2009 Jul 17;4(7):557-66.

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