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首页-小分子抑制剂&激动剂-Others-Other Targets-CPN-351 TFA
CPN-351 TFA

Chemical Structure : CPN-351 TFA

CAS No.:

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CPN-351 TFA

货号: PC-26902Not For Human Use, Lab Use Only.

CPN-351 TFA is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively.

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10 mg ￥2480 In stock
25 mg ￥4280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CPN-351 TFA is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively.

物理化学性质&存储条件

分子量 1026.15
分子式 C47H62F3N13O8S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-1-(((S)-2-((S)-3-(1H-indol-3-yl)-2-(N-methyl-2-(thiophen-2-yl)acetamido)propanamido)-2-methyl-3-phenylpropanoyl)-L-arginyl)-N-((S)-1-amino-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide trifluoroacetate

参考文献

1. Kentaro Takayama, et al. ACS Med Chem Lett. 2024 May 24;15(6):885-891.

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