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CPN-116

Chemical Structure : CPN-116

CAS No.: 1620490-70-1

CPN-116 (CPN116)

货号: PC-26871Not For Human Use, Lab Use Only.

CPN-116 is a potent, speciofic peptidic agonist of human neuromedin U receptor type 2 (NMUR2) with EC50 of 6.4 nM in calcium mobilization assays, significantly suppresses body weight gain in mice.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CPN-116 is a potent, speciofic peptidic agonist of human neuromedin U receptor type 2 (NMUR2) with EC50 of 6.4 nM in calcium mobilization assays, significantly suppresses body weight gain in mice.

物理化学性质&存储条件

分子量 835.05
分子式 C39H70N12O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Leu-Leu-{DAP}-Pro-Arg-{Asn(N-(3-cyclohexyl-1-oxopropyl))}

参考文献

1. Miyazato M, et al. Bioorg Med Chem. 2020 May 15;28(10):115454.

2. Tanaka A, et al. Mol Pharm. 2020 Jan 6;17(1):32-39.

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