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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-GSK-3-CP21R7
CP21R7

Chemical Structure : CP21R7

CAS No.: 125314-13-8

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CP21R7 (CP21)

货号: PC-42083Not For Human Use, Lab Use Only.

CP21R7 is a high-affinity, selective GSK3β inhibitor with IC50 of 1.8 nM, activates canonical Wnt signaling.

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10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CP21R7 is a high-affinity, selective GSK3β inhibitor with IC50 of 1.8 nM, activates canonical Wnt signaling.
CP21R7 also shows inhibitory activitiy against PKCα with IC50 of 1.9 uM.
CP21R7 promotes rapid and efficient differentiation of human pluripotent stem cells (hPSCs) into vascular endothelial and smooth muscle cells.

物理化学性质&存储条件

分子量 317.3413
分子式 C19H15N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 32 mg/mL
Chemical Name/SMILES

1H-Pyrrole-2,5-dione, 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-

参考文献

1. Patsch C, et al. Nat Cell Biol. 2015 Aug;17(8):994-1003.

2. Sahara M, et al. Cell Res. 2014 Jul;24(7):820-41.

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