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CP-20-I

Chemical Structure : CP-20-I

CAS No.:

CP-20-I

货号: PC-26394Not For Human Use, Lab Use Only.

CP-20-I is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 180 nM in group-I S. aureus transcriptional reporter assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CP-20-I is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 180 nM in group-I S. aureus transcriptional reporter assays.
CP-20-I could potentially target the AgrC sensor domain in both S. epidermidis and S. aureus (∼30–40% conserved across species).

物理化学性质&存储条件

分子量 510.37
分子式 C18H15IN4O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-iodophenyl)-2-(thiophene-3-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxamide

参考文献

1. Polaske TJ, et al. J Am Chem Soc. 2026 Mar 11;148(9):9199-9204.

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