CNX-774 | BTK inhibitor | Probechem Biochemicals

Chemical Structure : CNX-774

CAS No.: 1202759-32-7

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货号: PC-38625Not For Human Use, Lab Use Only.

CNX-774 (CNX774) is a potent, selective orally active, irreversible BTK inhibitor with IC50 of <1 nM, covalently targets Cys481 of BTK.

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CNX-774 (CNX774) is a potent, selective orally active, irreversible BTK inhibitor with IC50 of <1 nM, covalently targets Cys481 of BTK.

分子量	499.50
分子式	C26H22FN7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide

1. Akinleye A, et al. J Hematol Oncol. 2013 Aug 19;6:59.

2. Smiljkovic D, et al. Allergy. 2017 Nov;72(11):1666-1676.