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首页-小分子抑制剂&激动剂-Others-Other Targets-CNT2198
CNT2198

Chemical Structure : CNT2198

CAS No.:

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CNT2198 (CNT-2198)

货号: PC-26802Not For Human Use, Lab Use Only.

CNT2198 is a potent, selective dihydroceramide desaturase 1 (DES1) inhibitor, lowers renal ceramides, increases dihydroceramides, and shifts complex sphingolipid saturation without evidence of off-target effects.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CNT2198 is a potent, selective dihydroceramide desaturase 1 (DES1) inhibitor, lowers renal ceramides, increases dihydroceramides, and shifts complex sphingolipid saturation without evidence of off-target effects.

物理化学性质&存储条件

分子量 367.33
分子式 C16H16F3N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(5-hydroxypyridin-2-yl)-4-(6-(trifluoromethyl)pyridin-3-yl)piperazine-1-carboxamide

参考文献

1. Nicholson RJ, et al. Cell Metab. 2026 Jan 6;38(1):135-156.e10.

2. Patent US-20200339535-A1.

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