CMPDA

Chemical Structure : CMPDA

CAS No.: 380607-77-2

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货号: PC-43077Not For Human Use, Lab Use Only.

CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.

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CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.
CMPDA binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

物理化学性质&存储条件

分子量	376.5345
分子式	C16H28N2O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI)

参考文献

1. Weeks AM, et al. Neuropharmacology. 2014 Oct;85:57-66.

2. Timm DE, et al. Mol Pharmacol. 2011 Aug;80(2):267-80.

CMPDA

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CMPDA

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