CMC2.24 |CAS:1255639-43-0 Probechem Biochemicals

Chemical Structure : CMC2.24

CAS No.: 1255639-43-0

加入收藏

CMC2.24 (TRB-N0224)

货号: PC-63506Not For Human Use, Lab Use Only.

CMC2.24 (TRB-N0224) is a novel tricarbonylmethane agent that inhibits the Ras-RAF-MEK-ERK pathway, inhibits Ras activation in pancreatic cancer both in vitro and in vivo.

规格	价格	库存
5 mg	￥2780	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CMC2.24 (TRB-N0224) is a novel tricarbonylmethane agent that inhibits the Ras-RAF-MEK-ERK pathway, inhibits Ras activation in pancreatic cancer both in vitro and in vivo.
CMC2.24 inhibits Ras-GTP in MIA PaCa-2 cells and in pancreatic acinar explants isolated from KRas mutant mice.
CMC2.24 inhibits ERK1/2 activation in pancreatic cancer cells and xenografts, inhibits pancreatic cancer growth, inhibits the growth of pancreatic cancer xenografts.

物理化学性质&存储条件

分子量	427.456
分子式	C26H21NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2E,4E)-3-hydroxy-5-(4-hydroxyphenyl)-2-((E)-3-(4-hydroxyphenyl)acryloyl)-N-phenylpenta-2,4-dienamide

参考文献

1. Mallangada NA, et al. Mol Carcinog. 2018 Apr 23. doi: 10.1002/mc.22830.

CMC2.24 (TRB-N0224)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CMC2.24 (TRB-N0224)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.