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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Hedgehog (Hh)-CMAP compound 5
CMAP compound 5

Chemical Structure : CMAP compound 5

CAS No.: 1582736-30-8

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CMAP compound 5 (CMAP5)

货号: PC-23367Not For Human Use, Lab Use Only.

CMAP compound 5 (CMAP5) is a potent, small molecule Hedgehog pathway inhibitor with EC50 of 0.02 uM, blocks pathway signaling in a Smo-independent manner, activates GPR39.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CMAP compound 5 (CMAP5) is a potent, small molecule Hedgehog pathway inhibitor with EC50 of 0.02 uM, blocks pathway signaling in a Smo-independent manner, activates GPR39.

物理化学性质&存储条件

分子量 491.61
分子式 C25H29N7O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Cyano-N-[[trans-4-[[[4-(methylamino)-6-(2-pyridinyl)-2-pyrimidinyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide

参考文献

1. Bassilana F, et al. Nat Chem Biol. 2014 May;10(5):343-9.

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