CLK inhibitor T3 |CAS:2109805-56-1 Probechem Biochemicals

Chemical Structure : CLK inhibitor T3

CAS No.: 2109805-56-1

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CLK inhibitor T3 (T3-CLK, CLK-T3)

货号: PC-61021Not For Human Use, Lab Use Only.

CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively.

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10 mg	￥1780	In stock
25 mg	￥2980	In stock
50 mg	￥4980	In stock
100 mg		Get quote

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生物&药学活性

CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively.
CLK inhibitor T3 (T3) displays 200-300-fold selectivity over other dual specificity kinases such as DYRK1A and DYRK1B.
CLK inhibitor T3 (T3) induces dose-dependent reduction in exon recognition and exhibits an overlapping, but greater effect on transcriptome splicing compared to KH-CB19.

物理化学性质&存储条件

分子量	482.588
分子式	C28H30N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-methyl-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl)-N-(6-(pyridin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide

参考文献

1. Funnell T, et al. Nat Commun. 2017 Feb 23;8(1):7.

CLK inhibitor T3 (T3-CLK, CLK-T3)

生物&药学活性

物理化学性质&存储条件

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CLK inhibitor T3 (T3-CLK, CLK-T3)

生物&药学活性

物理化学性质&存储条件

参考文献

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