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首页-抗体药物偶连体和PROTACs-Drug-Linker Conjugates-CL2A-SN-38
CL2A-SN-38

Chemical Structure : CL2A-SN-38

CAS No.: 1279680-68-0

CL2A-SN-38

货号: PC-38053Not For Human Use, Lab Use Only.

CL2A-SN-38 is a drug-linker conjugate composed of the potent DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to construct antibody drug conjugate (ADC).

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10 mg ¥1280 In stock
25 mg ¥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CL2A-SN-38 is a drug-linker conjugate composed of the potent DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to construct antibody drug conjugate (ADC).

物理化学性质&存储条件

分子量 1738.506
分子式 C77H101Cl4N11O26
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((S)-2-(4-aminobutyl)-35-(4-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carboxamido)methyl)-1H-1,2,3-triazol-1-yl)-4,8-dioxo-6,12,15,18,21,24,27,30,33-nonaoxa-3,9-diazapentatriacontanamido)benzyl ((S)-4,11-diethyl-9-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl) carbonate bis(2,2-dichloroacetate)

参考文献

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