CL075 (3M002) | TLR8 agonist | Probechem Biochemicals

Chemical Structure : CL075

CAS No.: 256922-53-9

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CL075 (CL-075, 3M002, 3M-002)

货号: PC-70302Not For Human Use, Lab Use Only.

CL075 (3M002) is a selective TLR8 agonist that induces activation of NF-κB at 0.4 uM.

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10 mg	￥1580	In stock
25 mg	￥2580	In stock
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生物&药学活性

CL075 (3M002) is a selective TLR8 agonist that induces activation of NF-κB at 0.4 uM.
CL075 induces similar cytokine profiles from human PBMC compared with TLR8 agonist ssRNA.
CL075 effectively stimulates IL-12 production from mDC, but not pDC.
CL075 induces TNF-α and IL-12 at 0.1 uM from monocytes and monocyte-derived DC (Mo-DC).

物理化学性质&存储条件

分子量	243.33
分子式	C13H13N3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-propylthiazolo[4,5-c]quinolin-4-amine

参考文献

1. Gorden KB, et al. J Immunol. 2005 Feb 1;174(3):1259-68.

2. Spranger S, et al. J Immunol. 2010 Jul 1;185(1):738-47.

3. Makni-Maalej K, et al. J Leukoc Biol. 2015 Jun;97(6):1081-7.

CL075 (CL-075, 3M002, 3M-002)

生物&药学活性

物理化学性质&存储条件

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CL075 (CL-075, 3M002, 3M-002)

生物&药学活性

物理化学性质&存储条件

参考文献

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