CK-666 | Arp2/3 inhibitor | Probechem Biochemicals

Chemical Structure : CK-666

CAS No.: 442633-00-3

加入收藏

CK-666 (CK666, CK 0944666)

货号: PC-62458Not For Human Use, Lab Use Only.

CK-666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM, inhibits actin polymerization with either BtArp2/3 complex (IC50=17 uM) or SpArp2/3 complex (IC50=5 uM).

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3680	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CK-666 (CK 0944666) is a small molecule Arp2/3 complex inhibitor with IC50 of 4 uM, inhibits actin polymerization with either BtArp2/3 complex (IC50=17 uM) or SpArp2/3 complex (IC50=5 uM).
CK-666 reduces actin polymerization around intracellular Listeria to background levels at lower concentrations than CK-636.
CK-666 alters the morphology and slightly slowed but did not stop the gliding motility of fish keratocytes

物理化学性质&存储条件

分子量	296.345
分子式	C18H17FN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

参考文献

1. Hetrick B, et al. Chem Biol. 2013 May 23;20(5):701-12.

2. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

3. Yi K, et al. Nat Cell Biol. 2011 Aug 28;13(10):1252-8.

CK-666 (CK666, CK 0944666)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CK-666 (CK666, CK 0944666)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.