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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Arp2/3 complex-CK-636
CK-636

Chemical Structure : CK-636

CAS No.: 442632-72-6

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CK-636 (CK636, CK-0944636, CK0944636)

货号: PC-44784Not For Human Use, Lab Use Only.

CK-636 (CK-0944636) is a small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM).

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10 mg ￥580 In stock
25 mg ￥980 In stock
50 mg ￥1480 In stock
100 mg ￥2380 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CK-636 (CK-0944636) is a small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM).
CK-636 inhibits formation of actin filament comet tails by Listeria and podosomes by monocytes.

物理化学性质&存储条件

分子量 284.376
分子式 C16H16N2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 49 mg/mL
Chemical Name/SMILES

2-Thiophenecarboxamide, N-[2-(2-methyl-1H-indol-3-yl)ethyl]-

参考文献

1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

2. Zhou K, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-9.

3. Weeks HP, et al. Anticancer Res. 2016 Mar;36(3):1135-42.

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