Chemical Structure : CK-548
货号: PC-23089Not For Human Use, Lab Use Only.
CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.
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CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.
分子量 | 384.67 | |
分子式 | C15H11BrClNO2S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.
2. Yamagishi Y, et al. Biochem Biophys Res Commun. 2018 Feb 12;496(3):834-839.
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