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CK-548

Chemical Structure : CK-548

CAS No.: 388604-55-5

CK-548 (CK-0993548, CK548)

货号: PC-23089Not For Human Use, Lab Use Only.

CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.

物理化学性质&存储条件

分子量 384.67
分子式 C15H11BrClNO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-Bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-4-thiazolidinone

参考文献

1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

2. Yamagishi Y, et al. Biochem Biophys Res Commun. 2018 Feb 12;496(3):834-839.

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