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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Lipoxygenase-CJ-13610
CJ-13610

Chemical Structure : CJ-13610

CAS No.: 179420-17-8

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CJ-13610 (CJ13610)

货号: PC-62454Not For Human Use, Lab Use Only.

CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.

规格 价格 库存 数量
5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
CJ-13610 demonstrates antihyperalgesic activity in inflammatory pain models including the acute carrageenan model and the chronic inflammatory model.

物理化学性质&存储条件

分子量 393.505
分子式 C22H23N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

参考文献

1. Fischer L, et al. Br J Pharmacol. 2004 Jul;142(5):861-8.

2. Cortes-Burgos LA, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):59-67.

3. von Knethen A, et al. Cell Signal. 2013 Dec;25(12):2762-8.

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