Chemical Structure : CIQ
CAS No.: 486427-17-2
货号: PC-45533Not For Human Use, Lab Use Only.
CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
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---|---|---|---|
10 mg | ¥1280 | In stock | |
25 mg | ¥2180 | In stock | |
50 mg | ¥3580 | In stock | |
100 mg | Get quote |
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CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
CIQ enhances receptor responses two-fold with an EC50 of 3 uM by increasing channel opening frequency without altering mean open time or EC50 values for glutamate or glycine.
CIQ reverses MK-801-induced impairment in prepulse inhibition and working memory in Y-maze test in mice.
分子量 | 467.9413 | |
分子式 | C26H26ClNO5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Methanone, (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]- |
1. Mullasseril P, et al. Nat Commun. 2010 Oct 5;1:90.
2. Suryavanshi PS, et al. Br J Pharmacol. 2014 Feb;171(3):799-809.
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