欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-CIQ
CIQ

Chemical Structure : CIQ

CAS No.: 486427-17-2

CIQ (NR2C/2D-NMDAR potentiator)

货号: PC-45533Not For Human Use, Lab Use Only.

CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.

规格 价格 库存 数量
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg ¥3580 In stock
100 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
CIQ enhances receptor responses two-fold with an EC50 of 3 uM by increasing channel opening frequency without altering mean open time or EC50 values for glutamate or glycine.
CIQ reverses MK-801-induced impairment in prepulse inhibition and working memory in Y-maze test in mice.

物理化学性质&存储条件

分子量 467.9413
分子式 C26H26ClNO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methanone, (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-

参考文献

1. Mullasseril P, et al. Nat Commun. 2010 Oct 5;1:90.

2. Suryavanshi PS, et al. Br J Pharmacol. 2014 Feb;171(3):799-809.

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: