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首页-小分子抑制剂&激动剂-Others-Amyloids-CID 9998128
CID 9998128

Chemical Structure : CID 9998128

CAS No.: 733807-13-1

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CID 9998128 (CID9998128)

货号: PC-35140Not For Human Use, Lab Use Only.

CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.
    CID 9998128 strongly binds to both amyloid beta 42 (Aβ42) fibrils and β-secretase and the van der Waals interaction is dominating over the electrostatic interaction in binding affinity.

    物理化学性质&存储条件

    分子量 352.401
    分子式 C21H16N6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine

    参考文献

    1. Thai NQ, et al. ACS Chem Neurosci. 2018 May 18. doi: 10.1021/acschemneuro.8b00091.

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