CIB-Q22

Chemical Structure : CIB-Q22

加入收藏

货号: PC-27060Not For Human Use, Lab Use Only.

CIB-Q22 is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 1.74 nM, suppresses HCC cell viability (IC50=25.18 nM).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CIB-Q22 is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 1.74 nM, suppresses HCC cell viability (IC50=25.18 nM).
CIB-Q22 suppressed HCC proliferation and metastasis by inducing apoptosis and ferroptosis.
CIB-Q22 promoted mitochondrial oxidative stress and inhibited glycolysis, thereby sensitizing cells to glutamine deprivation.
CIB-Q22 exhibited comparable antitumor efficacy but improved safety compared to sorafenib.

物理化学性质&存储条件

分子量	335.38
分子式	C18H22FNO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-fluoro-6-methoxy-3-(3,4,5-trimethoxyphenethyl)aniline

参考文献

1. Zeen Qiao, et al. J Med Chem. 2026 Jun 12. doi: 10.1021/acs.jmedchem.6c00075.

CIB-Q22

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CIB-Q22

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.