CIB-3b | TRBP-Dicer inhibitor | Probechem Biochemicals

Chemical Structure : CIB-3b

CAS No.: 124811-87-6

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CIB-3b (TRBP-Dicer inhihitor)

货号: PC-38904Not For Human Use, Lab Use Only.

CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.

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10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2380	In stock
100 mg		Get quote

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生物&药学活性

CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
CIB-3b directly binds to transactivation response (TAR) RNA-binding protein 2 (TRBP), altering the activity of Dicer and mature miRNA production.

物理化学性质&存储条件

分子量	261.277
分子式	C14H15NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate

参考文献

1. Peng T, et al. J Med Chem. 2022 Aug 25;65(16):11010-11033.

CIB-3b (TRBP-Dicer inhihitor)

生物&药学活性

物理化学性质&存储条件

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CIB-3b (TRBP-Dicer inhihitor)

生物&药学活性

物理化学性质&存储条件

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