CHR-3464 | p38α inhibitor | Probechem Biochemicals

Chemical Structure : CHR-3464

加入收藏

货号: PC-24997Not For Human Use, Lab Use Only.

CHR-3464 is a potent, selective p38α MAPK inhibitor with IC50 of 1.86 nM, inhibits the production of TNF-α from THP-1 cells with IC50 of 1.5 nM.

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CHR-3464 is a potent, selective p38α MAPK inhibitor with IC50 of 1.86 nM, inhibits the production of TNF-α from THP-1 cells with IC50 of 1.5 nM.

分子量	362.28
分子式	C18H10F4N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-amino-5-(2,4-difluorobenzoyl)-1-(2,6-difluorophenyl)pyridin-2(1H)-one

1. Needham LA, et al. J Pharmacol Exp Ther. 2011 Oct;339(1):132-42.

2. Charlton, Michael H, et al. MedChemComm (2012), 3(9), 1070-1076.