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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-CHIP ligand 5
CHIP ligand 5

Chemical Structure : CHIP ligand 5

CAS No.:

CHIP ligand 5

货号: PC-25378Not For Human Use, Lab Use Only.

CHIP ligand 5 is potent, small molecule ligand of E3 ligase STUB1 (C-terminus of Hsc70-interacting protein, CHIP) with FP Kd value of 8.92 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CHIP ligand 5 is potent, small molecule ligand of E3 ligase STUB1 (C-terminus of Hsc70-interacting protein, CHIP) with FP Kd value of 8.92 uM.

物理化学性质&存储条件

分子量 421.41
分子式 C17H19F4N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N,N-dimethyl-1-(1-(4,5,6,7-tetrafluoro-1H-indole-3-carbonyl)piperidin-3-yl)methanesulfonamide

参考文献

1. Lucas SCC, et al. ACS Med Chem Lett. 2025 Aug 5;16(8):1445-1451.

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