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CHIKV inhibitor 26

Chemical Structure : CHIKV inhibitor 26

CAS No.: 2568903-91-1

CHIKV inhibitor 26

货号: PC-23568Not For Human Use, Lab Use Only.

CHIKV inhibitor 26 is a potent Chikungunya virus (CHIKV) inhibitor with viral titer reduction EC90 of 0.45 uM, inhibits alphavirus replication by blocking subgenomic viral RNA translation and structural protein synthesis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CHIKV inhibitor 26 is a potent Chikungunya virus (CHIKV) inhibitor with viral titer reduction EC90 of 0.45 uM, inhibits alphavirus replication by blocking subgenomic viral RNA translation and structural protein synthesis.

物理化学性质&存储条件

分子量 443.54
分子式 C23H17N5OS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(3-((4-cyanophenyl)amino)phenyl)thiazol-2-yl)-2-(methylthio)nicotinamide

参考文献

1. Garzan A, et al. J Med Chem. 2024 Dec 2. doi: 10.1021/acs.jmedchem.4c01073.

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