CHI3L1 inhibitor 30

Chemical Structure : CHI3L1 inhibitor 30

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货号: PC-21914Not For Human Use, Lab Use Only.

CHI3L1 inhibitor 30 is a potent, selective chitinase-3-like-1 (CHI3L1, YKL-40) inhibitor with IC50 of 50 nM, with little to no activity against hCHIT1 and hAMCase (IC50=6500 and 964 nM).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

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生物&药学活性

CHI3L1 inhibitor 30 is a potent, selective chitinase-3-like-1 (CHI3L1, YKL-40) inhibitor with IC50 of 50 nM, with little to no activity against hCHIT1 and hAMCase (IC50=6500 and 964 nM).

物理化学性质&存储条件

分子量	420.38
分子式	C22H27Cl2N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,5S)-5-(4-chlorobenzyl)-4-(1-(4-chloropyridin-2-yl)piperidin-4-yl)-2-methylmorpholine

参考文献

1. Czestkowski W, et al. J Med Chem. 2024.