CHDI-00484077 | class IIa HDAC inhibitor | Probechem Biochemicals

Chemical Structure : CHDI-00484077

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CHDI-00484077 (CHDI00484077)

货号: PC-27701Not For Human Use, Lab Use Only.

CHDI-00484077 is a selective class IIa HDAC inhibitor with IC50 of 0.01, 0.02, 0.02, and 0.03 uM for HDACX4, 5, 7 and 9 respectively, shows >100-fold selectivity over class I/IIb HDACs.

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生物&药学活性

CHDI-00484077 is a selective class IIa HDAC inhibitor with IC50 of 0.01, 0.02, 0.02, and 0.03 uM for HDACX4, 5, 7 and 9 respectively, shows >100-fold selectivity over class I/IIb HDACs.

物理化学性质&存储条件

分子量	382.39
分子式	C18H21F3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide

参考文献

1. Andrew J Stott, et al. ACS Med Chem Lett. 2021 Feb 11;12(3):380-388.

CHDI-00484077 (CHDI00484077)

生物&药学活性

物理化学性质&存储条件

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CHDI-00484077 (CHDI00484077)

生物&药学活性

物理化学性质&存储条件

参考文献

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