CHD1Li 11 | CHD1L inhibitor | Probechem Biochemicals

Chemical Structure : CHD1Li 11

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CHD1Li 11 (CHD1L inhibitor 11)

货号: PC-21580Not For Human Use, Lab Use Only.

CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM.

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生物&药学活性

CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM.
CHD1Li 11 displays cytotoxicity with IC50 of 3.3 uM against SW620 tumor organoids.
CHD1Li 11 inhibits CSC stemness in CRC cells with IC50 of 0.34 uM.
CHD1Li 11 effectively reduces metastatic potential of aggressive mesenchymal tumor cells.

物理化学性质&存储条件

分子量	285.32
分子式	C16H16FN3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(tert-butyl)-3-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one

参考文献

1. Sophia Clune, et al. Biomed Pharmacother. 2023 Dec 20:170:116037.

CHD1Li 11 (CHD1L inhibitor 11)

生物&药学活性

物理化学性质&存储条件

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CHD1Li 11 (CHD1L inhibitor 11)

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物理化学性质&存储条件

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